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KETAMINE

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Substance

Ketamine (ketamine hydrochloride) is a synthetic anesthetic and belongs to the class of hallucinogens, specifically a dissociative. It exerts its psychoactive effects primarily by blocking certain glutamate receptors. The effects are highly dependent on the amount consumed. Ketamine is used in psychiatry as a fast-acting antidepressant for treatment-resistant depression. [1]

group

Dissociatives

Forms of appearance

Liquid as a solution or as a white, crystalline powder.

Consumption patterns

Sniffed, swallowed or injected (intramuscularly or intravenously).

dosage

Ketamine is used as a party drug, usually in low doses, but in higher doses it can induce strong out-of-body, psychedelic experiences ("K-hole"). The dosage of ketamine depends heavily on the desired effect. In a party setting, usually only a few milligrams are snorted to achieve the desired effect. A higher dose results in a more intense effect and is not recommended in a party setting.

Be careful when mixing substances!

  • alcohol

  • Codeine

  • GHB / GBL

  • heroin

  • Opioids (painkillers)

  • Benzodiazepines

Substance groups

Effect

The main psychotropic effects are hallucinations and dissociative states. A fragmented dissolution of the environment and bodily sensations is possible; thoughts may become intermittent, and feelings of weightlessness or floating may occur. Sensory perceptions and the perception of space and time are altered. At higher doses, detachment from one's own body and/or ego dissolution or merging with the environment can occur, which some users describe as a near-death experience. A mild hallucinogenic effect usually sets in during the comedown. [1]

Onset of action

Snorted after 5–10 min., swallowed after 15–20 min., injected intramuscularly within 2–5 min., intravenously 1–3 min.

Duration of effect

Depending on the dose and method of consumption, 45 minutes to 2 hours (oral)

Aftereffects

1 hour (nasal) to 8 hours (oral)

Risks and side effects

Movement and communication can be severely impaired. Partial or complete numbness to pain, impaired coordination, restricted mobility, weakness, loss of appetite, nausea, vomiting, uncoordinated muscle movements, dizziness, impaired communication, slurred speech, increased heart rate and blood pressure, and cardiac arrhythmias are possible. At high doses: muscle rigidity, paralysis, and anesthesia; at very high doses: seizures and coma. Ketamine puts a strain on the cardiovascular system.

Long-term risks

A ketamine trip can be very psychologically stressful. Many ketamine users report near-death experiences, nightmare hallucinations, tunnel vision, blackouts, and brief periods of memory loss. After repeated use within a short period, tolerance develops and the effects diminish.

Safer Use

  • Ketamine is not a party drug. If you do use it at a party, use a low dose (max. 50 mg nasally / 100 mg orally).

  • Ketamine on the black market is usually a racemate, i.e. a mixture between S- and R-ketamine (S-ketamine is twice as potent as R-ketamine).

  • Never take ketamine alone and ensure you are in a familiar and comfortable environment.

  • Plan enough time to process the trip in peace afterwards.

  • Dose carefully and do not take ketamine on a full stomach.

  • You need a place to sit or lie down: Ketamine impairs your motor skills; at high doses, you may experience a fainting spell or pass out.

  • Because of the reduced pain sensitivity, you can injure yourself without noticing. Therefore, for example, dancing under higher doses of ketamine is not a good idea, as it can lead to bone fractures and tendon injuries that may not be immediately apparent.

  • People with cardiovascular problems, high blood pressure, bladder problems or glaucoma should absolutely avoid consuming ketamine!

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